Lofexidine - Isotope Labelled Standards
References
FAQ's
References
- Baganz, Horst; May, Hans J., Imidazoline derivatives and processes for the production thereof, US3966757A, Apr 8, 1975, Nordmark-Werke G.m.b.H. (https://www.lens.org/lens/search/patent/list?q=US3966757)
- Mastanamma, Sk; Satya, Anjali T.; Tejaswi, J.; Chiranmai, M.; Hema, Latha K., Separation and identification of forced degradation products of lofexidine by using LC-MS/MS, Asian Journal of Pharmaceutical and Clinical Research, Volume: 15, Issue: 9, Pages: 210-222, 2022 DOI: (10.22159/ajpcr.2022v15i9.45117)
Frequently Asked Questions
Under what conditions does Lofexidine degrade in the drug?
Lofexidine degrades under acid, alkaline hydrolysis, and oxidative conditions in the drug.
How do nitrosamine impurities form in the Lofexidine drug?
Amines and nitrates are the root cause of forming nitrosamine impurities in Lofexidine.
Why is it necessary to remove Lofexidine impurities from the drug?
Lofexidine impurities can affect drug safety and quality and pose health risks, so it is necessary to remove them from the drug.
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