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Home > Isotope Labelled Standards > Midodrine

Midodrine - Isotope Labelled Standards

Midodrine Labelled Standard
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Midodrine Labelled Standard

  • CAT Number DCTI-A-040
  • CAS Number 1188265-43-1
  • Molecular Formula C12H13D6ClN2O4 (HCl Salt) C12H12D6N2O4 (Free base)
  • Molecular Weight 296.78 (HCl Salt) 260.32 (Free base)
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References
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References

  1. Zoelss, Gerhard, 2-amino-n-method for producing (beta-hydroxy-phenaethyl)-acetamide-derivatives and of their salts, DE2506110C2, Feb 13, 1975, Lentia G.m.b.H. Chem. und Pharm. Erzeugnisse-Industriebedarf, Federal Republic of Germany (https://www.lens.org/lens/search/patent/list?q=DE2506110)
  2.  Posch, Werner; Lindner, Wolfgang, Quantification of midodrine and its active metabolite in plasma using a high-performance liquid chromatography column switching technique, Biomedical Chromatography, Volume: 3, Issue: 4, Pages: 153-6, 1989 DOI: (10.1002/bmc.1130030403)

Frequently Asked Questions

Contamination by raw materials, reagents, recovered solvents, catalysts, and the quenching process, is responsible for the formation of the nitrosamine Midodrine impurities.

A chiral RP-HPLC method helps identify Midodrine degradation products.

The nitrosamine Midodrine impurities can be carcinogenic and affect human health. Hence, it is essential to remove them from the drug.

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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