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Home > Isotope Labelled Standards > Sofosbuvir

Sofosbuvir - Isotope Labelled Standards
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Sofosbuvir-D6

  • CAT Number DCTI-A-032
  • CAS Number 1868135-06-1
  • Molecular Formula C22H23D6FN3O9P
  • Molecular Weight 535.49
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References
FAQ's

References

  1. Sofia, Michael J.; Bao, Donghui; Chang, Wonsuk; Du, Jinfa; Nagarathnam, Dhanapalan; Rachakonda, Suguna; Reddy, P. Ganapati; Ross, Bruce S.; Wang, Peiyuan; Zhang, Hai-Ren; et al, Discovery of a β-D-2'-Deoxy-2'-α-fluoro-2'-β-C-methyluridine Nucleotide Prodrug (PSI-7977) for the Treatment of Hepatitis C Virus, Journal of Medicinal Chemistry, Volume: 53, Issue: 19, Pages: 7202-7218, 2010
  1. Rezk, Mamdouh R.; Basalious, Emad B.; Karim, Iman A., Development of a sensitive UPLC-ESI-MS/MS method for quantification of sofosbuvir and its metabolite, GS-331007, in human plasma: Application to a bioequivalence study, Journal of Pharmaceutical and Biomedical Analysis, Volume: 114, Pages: 97-104, 2015

Frequently Asked Questions

Analytical Methods such as Reverse Phase-High Performance Liquid Chromatography (RP-HPLC) can detect impurities in Sofosbuvir.

Impurities in Sofosbuvir can impact patient safety. Depending on their nature and concentration, contaminants can cause adverse effects or reduce the efficacy of the medication.

Acetonitrile helps achieve optimal solubility and separation of Sofosbuvir impurities.

Sofosbuvir impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).

Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.

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