Flurbiprofen - Isotope Labelled Standards
References
FAQ's
References
- Adams S, Blancafort A, 2-(Mono-And Difluoro-4-Biphenyl)Propionic Acids, Boots Pure Drug Co., Ltd., Netherlands, US3755427A, August 28, 1973
- Kaiser, David G.; Shaw, S. Robert; Vangiessen, G. J., GLC [gas-liquid chromatography] determination of dl-2-(2-fluoro-4-biphenylyl)propionic acid (flurbiprofen) in plasma, Journal of Pharmaceutical Sciences, Volume: 63, Issue: 4, Pages: 567-70, 1974
Frequently Asked Questions
What is the purpose of synthesizing Flurbiprofen impurities?
Synthesis of Flurbiprofen impurities helps identify and quantify impurities in the drug substance or finished drug product, ensuring their safety and efficacy. Additionally, their synthesis helps in the development and optimization of the manufacturing process of the drug.
How are Flurbiprofen impurities detected and quantified?
The detection and quantification of impurities in Flurbiprofen involve analytical techniques such as high-performance liquid chromatography (HPLC) or liquid chromatography-mass spectrometry (LC-MS).
Which solvent is for the analysis of Flurbiprofen impurities?
The choice of solvent for analyzing impurities will depend on several factors, such as the chemical nature, the analytical technique used, and the desired sensitivity and selectivity of the analysis. Generally, a polar solvent like methanol helps in analyzing Flurbiprofen impurities.
What is the temperature required to store Flurbiprofen impurities?
Flurbiprofen impurities should be stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).
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