Amiodarone - NDSRI's
References
FAQ's
References
- Huang, Wenbo; Xu, Jing; Liu, Changhui; Chen, Zhiyan; Gu, Yanlong, Lewis Acid-Catalyzed Synthesis of Benzofurans and 4,5,6,7-Tetrahydrobenzofurans from Acrolein Dimer and 1,3-Dicarbonyl Compounds, Journal of Organic Chemistry, Volume: 84, Issue: 5, Pages: 2941-2950, 2019
- Flanagan, R. J.; Storey, G. C. A.; Holt, D. W., Rapid high-performance liquid chromatographic method for the measurement of amiodarone in blood plasma or serum at the concentrations attained during therapy, Journal of Chromatography, Volume: 187, Issue: 2, Pages: 391-8, 1980
Frequently Asked Questions
What methods help detect Amiodarone impurities?
High-performance liquid chromatography (HPLC) and mass spectrometry (MS) help detect and quantify Amiodarone impurities.
Do impurities in Amiodarone drug products cause drug interactions?
Impurities in Amiodarone drug products may cause drug interactions by altering the drug’s pharmacokinetics or interacting with other medicines.
How can Amiodarone impurities be controlled?
Strict manufacturing processes, proper storage conditions, and analytical testing to detect and quantify impurities can control Amiodarone impurities.
Which solvent helps in the analysis of Amiodarone impurities?
Methanol is a solvent used in analyzing many impurities in Amiodarone.
What are the temperature conditions required to store Amiodarone impurities?
Amiodarone impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).
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