Etomidate - NDSRI's
References
FAQ's
References
- Ellis, Edwin Owen; Beck, Peter Richard, Determination of etomidate in human plasma by high-performance liquid chromatography, Journal of Chromatography, Biomedical Applications, Volume: 232, Issue: 1, Pages: 207-11, 1982
- Shaw, J.; Kay, B.; Keegan, M.; Healy, T. E. J., Quantitative estimation of etomidate in water, plasma and blood. A comparison between high-performance liquid chromatography and gas chromatography, Journal of Pharmacological Methods, Volume: 7, Issue: 4, Pages: 311-19, 1982
Frequently Asked Questions
What are the potential risks associated with Etomidate impurities?
The potential risks associated with Etomidate impurities are toxicity and reduced efficacy of the drug causing harmful effects on patient's health.
How are Etomidate impurities detected and quantified?
Etomidate impurities can be detected and quantified using analytical techniques such as high-performance liquid chromatography (HPLC), gas chromatography (GC), and liquid chromatography-mass spectrometry (LC-MS).
Which solvent is used for the analysis of Etomidate impurities?
Methanol is commonly used for the analysis of Etomidate and its impurities. However, Acetonitrile is for tanalyzing impurities, such as Etomidate intermediate Nitroso impurity.
What are the temperature conditions required to store Etomidate impurities?
Etomidate impurities are stored at a controlled room temperature between 2-8 ⁰C or as indicated on the Certificate of Analysis (CoA).
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