Nadolol - NDSRI's
References
FAQ's
References
- Hauck, Frederic P.; Cimarusti, Christopher M.; Narayanan, Venkatachala L., Tetrahydronaphthyloxy-aminopropanols and salts thereof, US3935267A, Dec 1, 1971, R. Squibb and Sons, Inc. (https://www.lens.org/lens/search/patent/list?q=US3935267)
- Funke, Phillip T.; Malley, Mary F.; Ivashkiv, Eugene; Cohen, Allen I., Determination of serum nadolol levels by GLC-selected ion monitoring mass spectrometry: comparison with a spectrofluorometric method, Journal of Pharmaceutical Sciences, Volume: 67, Issue: 5, Pages: 653-7, 1978 DOI: (10.1002/jps.2600670521)
Frequently Asked Questions
What causes the formation of Nadolol impurities?
Side reactions and by-products formed during the synthetic process are the source of Nadolol impurities.
Which analytical method helps in identifying Nadolol impurities in the drug?
Ultra-high performance liquid chromatography coupled with mass spectrometry (UHPLC–MS) is the analytical method can identify Nadolol impurities in the drug.
Why is it essential to remove nitrosamine Nadolol impurities from the drug?
The nitrosamine Nadolol impurities can be carcinogenic and affect human health. Hence, it is essential to remove them from the drug.
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