Folic acid - NDSRI's
References
FAQ's
References
- Robert B. Angler et al. Synthesis of Pteroylglutamic Acid. III, J. Am. Chem. Soc. 1948, 70, 1, 25–26
- Williams, R. C.; Baker, D. R.; Schmit, J. A, Analysis of water-soluble vitamins by high-speed ion-exchange chromatography, Journal of Chromatographic Science, Volume: 11, Issue: 12, Pages: 618-24, 1973 DOI: (10.1093/chromsci/11.12.618)
Frequently Asked Questions
What are the different types of Folic acid impurities?
There are eight European Pharmacopeial impurities of Folic acid. In addition, two impurities occur due to photo-oxidation. Many known and unknown impurities of Folic acid are also present.
Which analytic methods detect Folic acid impurities?
Multidimensional NMR, FT-IR, UV-Vis, HRMS, and LC-MS are the analytical methods that help detect Folic acid impurities.
Why is it essential to isolate Folic acid impurities?
Isolation of Folic acid impurities helps in quality control and method validation during commercial production of Folic acid.
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