Phenylephrine - NDSRI's
References
FAQ's
References
- Legerlotz, H., A process for preparing m- and p-hydroxy-phenyl-n-methyl-amino-ethanol-1, GB354226A, July 27, 1931
- Montgomery, Kenneth O.; Jennings, P. V.; Weinswig, Melvin H., Ion-exchange separation and ultraviolet determination of phenylephrine, codeine, and selected antihistamines, Journal of Pharmaceutical Sciences, Volume: 56, Issue: 1, Pages: 141-3, 1967
Frequently Asked Questions
Can Phenylephrine impurities be removed?
Depending on the impurity and its concentration, purification techniques such as recrystallization, column chromatography, or other purification methods can be employed to remove or reduce them in Phenylephrine.
Are there regulatory guidelines for Phenylephrine impurities?
Regulatory authorities provide guidelines and limits for impurities in pharmaceutical substances, including Phenylephrine, to ensure product quality and safety.
What are the temperature conditions required to store Phenylephrine impurities?
Phenylephrine impurities are stored at a regulated room temperature of 2-8°C or as specified on the Certificate of Analysis (CoA).
Why are impurities a concern in Phenylephrine?
Impurities in Phenylephrine can have potential safety and efficacy implications. Some may be toxic or have undesirable effects on the body. They can also affect the stability and quality of the drug, potentially reducing its effectiveness or causing adverse reactions in patients.
Note: Products protected by valid patents by a manufacturer are not offered for sale in countries having patent protection. The sale of such products constitutes a patent infringement, and its liability is at the buyer's risk.