Avobenzone D3

General Information

Avobenzone Impurities and Avobenzone

Daicel Pharma offers superior-quality Avobenzone impurities and Avobenzone D3 Labelled Standard. It is vital for evaluating Avobenzone quality, stability, and biological safety. In addition, Daicel Pharma specializes in the custom synthesis of Avobenzone impurities and ensures their worldwide delivery.
Avobenzone [CAS: 70356-09-1] is a sunscreen agent. It blocks Ultraviolet (UVA I, UVA II, and UVB) wavelengths, protecting the skin from harmful UV rays. It is an oil-soluble ingredient used in many sunscreens.

Avobenzone: Use and Commercial Availability  

Avobenzone is part of sunscreen formulation. It is a UVA filter absorbing maximum UVA rays. As it is light-sensitive, photo stabilizers are added to the formulation to increase its stability and activity. Further, sunscreen agents reduce symptoms like premature skin aging and skin cancer. It is a broad-range UV protector and is sold as a topical formulation. It is available under brands Parsol 1789, Parsol A, Photoplex, Milestab 1789, etc.

Avobenzone Structure and Mechanism of Action

The chemical name of Avobenzone is 1-[4-(1,1-Dimethylethyl)phenyl]-3-(4-methoxyphenyl)-1,3-propanedione. The chemical formula for Avobenzone is C₂₀H₂₂O₃, and its molecular weight is approximately 310.39 g/mol.

Avobenzone absorbs UV radiation within a specific wavelength range and decreases ultraviolet (UV) light penetration through the epidermis.

Avobenzone Impurities and Synthesis

While synthesizing Avobenzone 1, impurities may form that will affect the safety and efficacy of the drug. These impurities form during Avobenzone synthesis, purification, storage, or degradation. Avobenzone impurities need control and monitoring to improve the drug’s safety, efficacy, and storage.
Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Avobenzone impurities and Avobenzone D3 Labelled Standard. A CoA is from a cGMP-compliant analytical facility. It contains the complete characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. We give additional spectral data on request. Daicel Pharma can prepare any unidentified Avobenzone impurity or degradation product. In addition, Daicel Pharma offers a highly purified, stable deuterium-labeled standard, such as the Avobenzone D3 Labelled Standard. A complete characterization report is available on delivery.