Cyclobenzaprine

General Information

Cyclobenzaprine Impurities and Cyclobenzaprine  

Daicel Pharma is a reliable source in synthesizing the best-quality Cyclobenzaprine impurities, such as Cyclobenzaprine 10,11-Epoxide and N-nitroso Cyclobenzaprine. They are vital for evaluating the quality, stability, and biological safety of Cyclobenzaprine. Furthermore, Daicel Pharma specializes in the custom synthesis of Cyclobenzaprine impurities and ensures their global delivery.

Cyclobenzaprine [CAS: 303-53-7] is a tricyclic amine compound acting as an antidepressant. It reduces skeletal muscle hyperactivity. It is usually used for short periods to relieve muscle spasms caused by acute, painful musculoskeletal conditions.

Cyclobenzaprine: Use and Commercial Availability  

Cyclobenzaprine treats painful muscle spasms in patients. It is a skeletal muscle relaxant. It improves the range of motion in patients by decreasing localized pain and tenderness. In addition, it acts as a centrally-acting depressant. Various manufacturers prepare Cyclobenzaprine. However, Cyclobenzaprine is available under Amrix and Flexeril as an oral formulation.

Cyclobenzaprine Structure and Mechanism of Action

The chemical name of Cyclobenzaprine is 3-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-N, N-dimethyl-1-propanamine. The chemical formula for Cyclobenzaprine is C20H21N, and its molecular weight is approximately 275.39 g/mol.

As a skeletal muscle relaxant, Cyclobenzaprine does not interfere with muscle functions. It acts within the central nervous system.

Cyclobenzaprine Impurities and Synthesis

While synthesizing Cyclobenzaprine1, impurities may form that will affect the safety and efficacy of the drug. They form during the synthetic process, purification, or storage of Cyclobenzaprine. Controlling and monitoring Cyclobenzaprine impurities is essential during the drug development process.

Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Cyclobenzaprine impurities, which includes Cyclobenzaprine 10,11-Epoxide and N-nitroso Cyclobenzaprine. Daicel Pharma offers CoA from a cGMP-compliant analytical facility. It provides complete characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. We give additional analytical data on request. Daicel Pharma can prepare any unidentified Cyclobenzaprine impurity or degradation product. Further, Daicel Pharma offers a highly purified, stable isotope-labeled standard of Cyclobenzaprine. The clients of Daicel Pharma can expect a complete characterization report on delivery.