Cyproterone Acetate

General Information

Cyproterone acetate Impurities and Cyproterone acetate  

Daicel Pharma is a reliable source in synthesizing excellent-quality Cyproterone acetate impurities and labeled standards. They are vital for evaluating the quality, stability, and biological safety of Cyproterone acetate. Furthermore, Daicel Pharma specializes in the custom synthesis of Cyproterone acetate impurities and ensures their global delivery.

Cyproterone acetate [CAS: 427-51-0] is a steroid ester, which is an antiandrogenic drug. It is a synthetic progesterone derivative. It suppresses androgens with progestogenic activity. Cyproterone acetate stops the growth of testosterone-sensitive tumor cells. It also acts as a contraceptive agent. It decreases the activity of 5α-reductase in the skin.

Cyproterone acetate: Use and Commercial Availability  

Cyproterone acetate treats patients with prostatic cancer. It is for contraceptive activity in males. It prevents the actions of androgens. Further, Cyproterone acetate with ethinyl estradiol treats women with severe acne and hirsutism. It is an oral formulation available under Cyproterone, Androcur, Cyprostat, etc.

Cyproterone acetate Structure and Mechanism of Action

The chemical name of Cyproterone acetate is (1β,2β)-17-(Acetyloxy)-6-chloro-1,2-dihydro-3′H-cyclopropa[1,2]pregna-1,4,6-triene-3,20-dione. The chemical formula for Cyproterone acetate is C24H29ClO4, and its molecular weight is approximately 416.94 g/mol.

Cyproterone acetate blocks the dihydrotestosterone binding to the specific receptors in the prostatic carcinoma cell. It inhibits the secretion of luteinizing hormone and causes lowered production of testicular testosterone.

Cyproterone acetate Impurities and Synthesis

During Cyproterone acetate synthesis1, impurities form that may affect the safety and efficacy of the drug. They form during the synthetic process, purification, or storage of Cyproterone acetate. Cyproterone acetate impurities must be controlled and monitored throughout the drug development process.

Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Cyproterone acetate impurities and labeled standards. Daicel Pharma offers CoA from a cGMP-compliant analytical facility. It provides complete characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity2. We give additional analytical data on request. Daicel Pharma can prepare any unidentified Cyproterone acetate impurity or degradation product. In addition, Daicel Pharma offers highly purified, stable deuterium-labeled standards, Cyproterone Acetate-13C2D3, and Cyproterone Acetate-D3. The clients of Daicel Pharma can expect a complete characterization report on delivery.