Diltiazem
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References
FAQ's
References
- Igarashi, Kikuo; Honma, Tsunetoshi, Process for production of Diltiazem hydrochloride, Shionogi and Co., Ltd., Japan, US4552695A, November 12, 1985
- Shimizu, Reiji; Ishii, Kazuhiro; Tsumagari, Nobuchika; Tanigawa, Masatoshi; Matsumoto, Mikio; Harrison, Ian T., Determination of optical isomers in diltiazem hydrochloride by high-performance liquid chromatography, Journal of Chromatography, Volume: 253, Issue: 1, Pages: 101-8, 1982
Frequently Asked Questions
How is the control of Diltiazem impurities ensured during the production process?
Stringent quality control measures, including regular testing and monitoring, are implemented to ensure the control of impurities during production.
Can impurity profiles in Diltiazem differ among different manufacturers?
Yes, impurity profiles may vary among different manufacturers due to differences in synthetic processes, raw materials, and manufacturing controls.
Which solvent helps in the analysis of Diltiazem impurities?
Methanol or Chloroform are the solvents used in analyzing many impurities in Diltiazem.
What are the temperature conditions required to store Diltiazem impurities?
Diltiazem impurities are stored at a controlled room temperature between 2-8 °C or as indicated on the Certificate of Analysis (CoA).
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