Mepivacaine

General Information

Mepivacaine Impurities and Mepivacaine

Daicel Pharma offers excellent-quality Mepivacaine impurities, such as Mepivacaine EP Impurity-D. They are vital for evaluating Mepivacaine quality, stability, and biological safety. In addition, Daicel Pharma specializes in the custom synthesis of Mepivacaine impurities and ensures worldwide delivery.

Mepivacaine [CAS: 96-88-8] is a carboxamide derivative and a local anesthetic. It is similar in properties to lidocaine, but its effect lasts for a longer duration. Mepivacaine inhibits neuronal sodium channels and is a nerve blocker when administering anesthesia.

Mepivacaine: Use and Commercial Availability  

Mepivacaine is available under Carbocaine as an injectable formulation. Many brands market Mepivacaine. It is a regional or local anesthetic. It is used in dental procedures in patients by nerve block or infiltration. Further, Mepivacaine can produce analgesia in patients. The dosage of Mepivacaine varies depending on the method, duration, and patient’s physical condition.

Mepivacaine Structure and Mechanism of Action

The chemical name of Mepivacaine is N-(2,6-Dimethylphenyl)-1-methyl-2-piperidinecarboxamide. The chemical formula for Mepivacaine is C₁₅H₂₂N₂O, and its molecular weight is approximately 246.35 g/mol.

Mepivacaine stops the formation and conduction of nerve impulses. It raises the electric excitation threshold in the nerve and decreases nerve impulse propagation.

Mepivacaine Impurities and Synthesis

During Mepivacaine synthesis1, impurities form that may affect drug safety and efficacy. They form during drug manufacture, purification, or storage. The impurities must be controlled and monitored throughout the drug development process.
Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Mepivacaine impurities, which includes Mepivacaine EP Impurity-D. We provide the CoA from a cGMP-compliant analytical facility. It gives complete characterization data2 such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity. We provide additional analytical data on request. Daicel Pharma can prepare any unidentified Mepivacaine impurity or degradation product. In addition, Daicel Pharma offers highly purified, stable isotope-labeled standards of Mepivacaine. The clients of Daicel Pharma can expect a complete characterization report on delivery.