Metaxalone

General Information

Metaxalone Impurities and Metaxalone

Daicel Pharma offers the best-quality Metaxalone impurities and labeled standards. They are vital for evaluating Metaxalone quality, stability, and biological safety. Furthermore, Daicel Pharma specializes in the custom synthesis of Metaxalone impurities and ensures their worldwide delivery.

Metaxalone [CAS: 1665-48-1] is an oxazolidinedione derivative. It is a skeletal muscle relaxant and has sedative properties. As it has central nervous system depressant actions, it benefits people with musculoskeletal symptoms.

Metaxalone: Use and Commercial Availability  

Metaxalone is a muscle relaxant but has no direct effect on muscle tissues. It treats chronic, acute, and inflammatory musculoskeletal disorders. It relieves pain from muscle spasms, sprains, and inflammation in patients. It is effective in treating spasticity associated with neurological disorders. It is available as an oral formulation under Skelaxin.

Metaxalone Structure and Mechanism of Action

The chemical name of Metaxalone is 5-[(3,5-Dimethylphenoxy)methyl]-2-oxazolidinone. The chemical formula for Metaxalone is C₁₂H₁₅NO₃, and its molecular weight is approximately 221.25 g/mol.

The exact mechanism of action of Metaxalone is unknown.

Metaxalone Impurities and Synthesis

During Metaxalone synthesis1, impurities form that may affect the drug’s safety and efficacy. These impurities form during the manufacturing process, purification, or storage of Metaxalone. Therefore, Metaxalone impurities must be controlled and monitored throughout the drug’s development.
Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Metaxalone impurities and labeled standards. We provide the CoA from a cGMP-compliant analytical facility. It gives complete characterization data2 such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity. We provide additional analytical data on request. Daicel Pharma can prepare any unidentified Metaxalone impurity or degradation product. In addition, Daicel Pharma offers a highly purified, stable deuterium-labeled standard, Metaxalone Labelled Standard. We provide a complete characterization report to clients on delivery.