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Oxytocin
References
FAQ's
References
- Vincent du Vigneaud, Charlotte Ressler, John M. Swan, Carleton W. Roberts, and Panayotis G. Katsoyannis, “The Synthesis of Oxytocin” Am. Chem. Soc.1954, 76, 12, 3115–3121, 98,1954
- Oxytocin-World Health Organization
- Frei, R. W.; Michel, L.; Santi, W; “Post-column fluorescence derivatization of peptides. Problems and potential in high-performance liquid chromatography”; Journal of Chromatography, Volume: 126, Pages: 665-77,1976
Frequently Asked Questions
What are the most common Oxytocin impurities?
The most common impurities may include Asp-5-oxytocin, des amino-Oxytocin, and oxidized Oxytocin. The specific impurities present may vary depending on the manufacturing process and other factors.
What are the methods used to identify Oxytocin impurities?
Methods used to identify Oxytocin impurities include high-performance liquid chromatography (HPLC), and liquid chromatography mass spectrometry (LC-MS).
How can Oxytocin impurities impact clinical trials and drug approval?
Oxytocin impurities may impact clinical trials and drug approval by affecting the safety and efficacy of the product. Further, the regulatory authorities may need additional testing or data to demonstrate the safety and quality of the product.
Can Oxytocin impurities be removed from the medication?
Oxytocin impurities are removed from the medication using purification techniques, such as reverse-phase high-performance liquid chromatography. However, it is ideal to minimize the formation of impurities during the manufacturing process.
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