Prochlorperazine

General Information

Prochlorperazine Impurities and Prochlorperazine

Daicel Pharma offers the best quality Prochlorperazine impurities, N-Nitroso Desmethyl Prochlorperazine. They are vital for evaluating the quality, stability, and biological safety of Prochlorperazine. Furthermore, Daicel Pharma specializes in the custom synthesis of Prochlorperazine impurities and ensures their worldwide delivery.

Prochlorperazine [CAS: 58-38-8] a phenothiazine derivative, helps in schizophrenia treatment and other psychotic symptoms. As an antipsychotic drug, Prochlorperazine treats conditions of mental illness. In addition, Prochlorperazine helps in treating patients suffering from nausea and vomiting after chemotherapy and radiation therapy.

Prochlorperazine: Use and Commercial Availability  

Prochlorperazine treats schizophrenia and its symptoms of hallucinations, agitation, delusions, etc. It also treats nausea and vomiting in patients before and after surgery. Further, it is helpful in the treatment of migraine. Prochlorperazine can be administered by routes-oral, intramuscular parenteral, and rectal. Thus, drug dosing and formulation also vary according to the medical conditions. Many generic manufacturers supply Prochlorperazine under different brand names. Some of them are Compro, Compazine, Procomp, etc.

Prochlorperazine Structure and Mechanism of Action

The chemical name of Prochlorperazine is 2-Chloro-10-[3-(4-methyl-1-piperazinyl)propyl]-10H-phenothiazine. The chemical formula for Prochlorperazine is C20H24ClN3S, and its molecular weight is approximately 373.94 g/mol.

Prochlorperazine inhibits D2 dopamine receptors, thus reducing psychotic symptoms.

Prochlorperazine Impurities and Synthesis

During the synthesis of Prochlorperazine , impurities may form that may affect the safety and efficacy of the drug. These impurities form during the synthesis, storage, or degradation of Prochlorperazine. So, Prochlorperazine impurities must be controlled and monitored throughout the drug’s lifecycle.

Daicel Pharma offers a comprehensive Certificate of Analysis (CoA) for Prochlorperazine impurities, which includes N-Nitroso Desmethyl Prochlorperazine. The issued CoA is from a cGMP-compliant analytical facility. It contains characterization data such as 1H NMR, 13C NMR, IR, MASS, and HPLC purity. We give additional spectral data on request.Daicel Pharma can prepare any unidentified Prochlorperazine impurity or degradation product. In addition, Daicel Pharma offers highly purified Stable isotope-labeled standards of Prochlorperazine for bioanalytical research and BA/BE studies. We also provide a complete characterization report on delivery.