Propranolol
References
- Crowther, A. F.; Smith, L. H., β-Adrenergic blocking agents. II. Propranolol and related 3-amino-1-naphthoxy-2-propanols, Journal of Medicinal Chemistry, Volume: 11, Issue: 5, Pages: 1009-13, 1968
- Di Salle, E.; Baker, K. M.; Bareggi, S. R.; Watkins, W. D.; Chidsey, C. A.; Frigerio, A.; Morselli, P. L., Sensitive gas chromatographic method for the determination of propranolol in human plasma, Journal of Chromatography, Volume: 84, Issue: 2, Pages: 347-53, 1973
Frequently Asked Questions
Is it safe to use Propranolol with impurities present?
The safety of using Propranolol depends on the nature and concentration of the impurities present. If impurity levels are within acceptable limits by regulatory authorities, the medication is generally considered safe.
How can Propranolol impurities be minimized during storage?
Propranolol should be stored according to the accurate synthesis instructions to minimize the formation of impurities during storage. Adhering to the recommended storage conditions helps maintain the drug's stability and minimizes impurity formation.
How are Propranolol impurities detected?
Impurities in Propranolol are detected using various analytical techniques, such as high-performance liquid chromatography (HPLC). These methods can accurately identify and quantify impurities present in the drug.
What are the temperature conditions required to store Propranolol impurities?
Propranolol impurities should be stored at a regulated room temperature of 2-8°C or as specified on the Certificate of Analysis (CoA).
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