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Arginine Vasopressin, Asp5-vasopressin, Gly9-vasopressin, Glu4-vasopressin, Dimeric-vasopressin, D-Asn-vasopressin, and N-Acetyl-Vasopressin are the impurities that commonly occur in Vasopressin. These impurities have properties that resemble those of the drug, which makes purification difficult.
Controlling Vasopressin impurities in the drug is vital to ensure the hormone's quality and purity and to reduce potential side effects or toxicity.
Vasopressin impurities can be detected using analytical methods such as high-performance liquid chromatography (HPLC) and mass spectrometry (MS)
Vasopressin synthetic steps include solid-phase peptide synthesis, purification, and characterization.
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